Goldenseal herb powder may look and taste different than the powdered root, but it contains the same active alkaloids, namely berberine and hydrastine, just in lesser amounts. The aerial parts of the herb contain something else that the root doesn’t – flavonoids that acts as efflux pump inhibitors. These molecules interrupt the activity of transport proteins that reside on the surface of bacteria cells that contribute to antibiotic resistance. Enjoy this goldenseal powder tinctured, in tea blends, or in capsule form.