Hydrangea is a genus of nearly 75 species of flowering shrubs of ancient
origin. In fact, evidence exists that hydrangea thrived in Asia as long as
25 million years ago and in North America more than 70 million years ago.
The herbal preparation referred to as hydrangea root is derived from smooth
hydrangea (Hydrangea arborescens), which is native to the eastern United
States. Also known as seven barks, this species of hydrangea has a long
history of use by Native Americans and early European settlers that is now
backed up by modern science.
The Cherokees used hydrangea root
to address skin irritations, burns and
wounds, as well as bladder and kidney stones. In fact, the traditional
“kidney stone tea” consists of hydrangea root,
cramp bark,
plantain leaf and
Joe Pye weed. In Chinese medicine,
hydrangea root has also been used for
centuries to treat stones of the bladder and kidneys and to counter malaria.
Japanese scientists have recently found that there may be merit to using
this herb to encourage the passing of small kidney stones.
Hydrangea root
appears to have a protective effect on the liver as well. In fact, a study
published in the Japanese medical journal Bioscience, Biotechnology, and
Biochemistry (BBB) in 2003 reported that hydrangea root
extracts deliver more antioxidant value to the liver than
milk thistle and
turmeric extracts
combined.
In the June 5, 2009 issue of Science, a team of researchers from the Program
in Cellular and Molecular Medicine and the Immune Disease Institute at
Children's Hospital Boston and another from the Harvard School of Dental
Medicine announced that hydrangea root
may play a role in the treatment of a
number of autoimmune disorders, including eczema, psoriasis, type 1
diabetes, multiple sclerosis, rheumatoid arthritis and inflammatory bowel
disease. Of particular interest is halofuginone, a molecule isolated from
hydrangea root.
In this particular study, the researchers found that
halofuginone blocked the production of pro-inflammatory chemicals
collectively referred to as cytokines. This substance also inhibited the
production of Th17, a specialized immune system helper cell thought to be
involved in triggering an inflammatory response that causes the immune
system to mistakenly attack healthy tissue.